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|Section2= |Section3= }} 2,5-Furandicarboxylic acid (FDCA), also known as ''dehydromucic acid'', is an oxidized furan derivative. This organic compound was first obtained by Fittig and Heinzelmann in 1876.〔van Putten, R-J., van der Waal J.C. de Jong, E., Rasrendra C.B., Heeres, E.J. and de Vries H.G. (2011) Furan-based platform chemicals of the future. Dehydration of hexoses as biosustainable product route. Chemical Reviews submitted.〕 The first review by Henry Hill was already published in 1901.〔Hill 1901 Am. Chem. Journ. 25, 439〕 FDCA has also been detected in human urine.〔Witten, T.A.; S.P. Levine, M. Killan, P. Boyle and S. Harkey. Clin. Chem. 1973, 19, 963〕 A healthy human produces 3–5 mg/day. Numerous studies were undertaken to establish the metabolism of this compound and to determine the quantity, which is produced depending on the healthiness of the human. It was demonstrated that the individual quantity of produced FDCA increased after the injection of fructose. FDCA was also detected in blood plasma.〔Lewkowski J. 2001, Synthesis, chemistry and applications of 5-hydroxymethyl-furfural and its derivatives. (ARKIVOC pp. 17-54 )〕 FDCA was more than 125 years later identified by the US Department of Energy as one of 12 priority chemicals for establishing the “green” chemistry industry of the future. Furan-2,5-dicarboxylic acid (FDCA) has been suggested as an important renewable building block because it can substitute for terephthalic acid (PTA) in the production of polyesters and other current polymers containing an aromatic moiety.〔〔T. Werpy, G. Petersen: ''Top Value Added Chemicals from Biomass. Volume I – Results of Screening for Potential Candidates from Sugars and Synthesis Gas.'' Produced by the Staff at Pacific Northwest National Laboratory (PNNL); National Renewable Energy Laboratory (NREL), Office of Biomass Program (EERE), 2004 ((Download ))〕〔Bozell JJ, Petersen Technology development for the production of biobased products from biorefinery carbohydrates—the US Department of Energy’s “Top 10” revisited. (Green Chem 2010;12:539–554 )〕 Avantium has announced plans to produce 40 ton/year of FDCA monomer at a pilot plant in the second half of 2011.〔(Avantium starts bio-polyester pilot plant ) ICIS Green Chemicals〕 ==Synthesis of FDCA== Methods for the synthesis of the FDCA may be divided into four groups:〔 * Dehydration of hexose derivatives * Oxidation of 2,5-disubstituted furans * Catalytic conversions of various furan derivatives * Biological conversion of HMF 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「2,5-Furandicarboxylic acid」の詳細全文を読む スポンサード リンク
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